TB-500
Also known as Thymosin Beta-4 fragment, TB4
Synthetic fragment related to Thymosin Beta-4 studied for tissue repair.
Medical status: Not approved as a medicine; banned in competitive sport.
Also commonly used for (off-label)
- Whole-body soft-tissue recovery
- Chronic or stubborn injuries
- Flexibility and range of motion
Off-label and research uses are what people report, not approved indications. Talk to a clinician before using any of them.
How it's taken
a small shot into the fat just under the skin (belly, thigh, or love handle)
a deeper shot into a muscle, usually the glute, thigh, or shoulder
Availability varies by supplier — injectable is the most commonly researched form.
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- Documented dose
- 1000–2500 mcg
- Typical frequency
- Twice weekly (loading), then as needed to maintain
- Cycle
- 8 weeks on, 4 off
- Half-life
- ~2-3 days (estimated)
- Common vial sizes
- 5 mg, 10 mg
- Regulatory status
- Not approved for human use; banned by WADA.
Dose on a U-100 syringe (1000–2500 mcg)
| Vial | BAC water | Draw |
|---|---|---|
| 5 mg | 1 mL | 20–50 units |
| 10 mg | 1.5 mL | 15–38 units |
| 10 mg | 2 mL | 20–50 units |
On a U-100 syringe, 100 units = 1 mL, and the syringe holds 100 units total. Most people keep a single subcutaneous injection under about 50 units — bigger volumes are usually mixed stronger (less water) or split into two shots. Only mixes that fit in one syringe are shown. Always double-check with the reconstitution calculator.
What it does
A synthetic version of an active piece of Thymosin Beta-4, a protein involved in cell movement and repair. It helps cells migrate into damaged areas and encourages new blood vessels to grow there. What people look into it for: • Muscle, tendon and ligament recovery after injury or hard training • Better flexibility and less scar-tissue stiffness • Wound healing and reduced inflammation • Heart tissue repair in animal research It is often paired with BPC-157: TB-500 works more systemically throughout the body while BPC-157 works strongly at the site of injury.
Mechanism
Binds G-actin and promotes actin polymerisation, cell migration and angiogenesis.
Storage — lyophilisedwhat's this?
Refrigerate 2-8C, protect from light.
Storage — reconstitutedwhat's this?
Refrigerate 2-8C, use within ~28 days.
Reconstitution noteswhat's this?
Common mix: 10 mg vial + 2 ml bacteriostatic water = 50 mcg per unit, so 1 mg is 20 units and 2.5 mg is 50 units. Most weekly totals land between 2 mg and 5 mg split over two or three days.
Stacks well with
- BPC-157Most common pairing: whole-body tissue repair plus targeted local healing.
- Thymosin Alpha-1Both thymus-derived; combined when immune support is part of the goal.
- IpamorelinGrowth hormone pulses are added to support recovery from injury.
Popular combinations reported in the community and research literature — not a recommendation. Adding peptides multiplies side-effect risk; check with a clinician.
Commonly reported side effects
- Fatigue after dosing
- Head rush
- Injection-site irritation
Contraindications noted
- Active malignancy (theoretical)
- Pregnancy or breastfeeding
Research notes
Human data limited; most claims extrapolated from animal wound-healing models.
Vendors carrying TB-500
These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.
- PeptideMaxxingpeptidemaxxing.com15% Off(opens in a new window)
- Nexaphnexaph.com(opens in a new window)
- Modified Aminosmodifiedaminos.shop(opens in a new window)
- ReadyPepreadypep.com15% Off(opens in a new window)
- Penguin Peptidespenguinpeptides.com(opens in a new window)
- Peplair Researchpeplairresearch.shop(opens in a new window)
- Biotech Peptidesbiotechpeptides.com(opens in a new window)
- Sports Technology Labssportstechnologylabs.com(opens in a new window)
- Core Peptidescorepeptides.com(opens in a new window)
- Value Research Labsvalueresearchlabs.com(opens in a new window)
- Zeptix Labszeptixlabs.com15% Off(opens in a new window)
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Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.