longevitysleepskin

Epitalon

Also known as Epithalon, AEDG

Tetrapeptide studied for telomerase activity and pineal regulation.

Medical status: Not approved as a medicine outside limited use in Russia.

Also commonly used for (off-label)

Longevity and telomere research
Sleep and circadian rhythm reset

Off-label and research uses are what people report, not approved indications. Talk to a clinician before using any of them.

How it's taken

Subcutaneous injection
a small shot into the fat just under the skin (belly, thigh, or love handle)
Nasal spray
sprayed into the nose and absorbed through the nasal lining — no needles

Availability varies by supplier — injectable is the most commonly researched form.

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Documented dose: 5–10 mg
Typical frequency: Once daily for 10–20 days, repeated 2–3 times per year
Cycle: 3 weeks on, 12 off
Half-life: ~30 minutes
Common vial sizes: 10 mg, 50 mg
Regulatory status: Not approved for human use.

Dose on a U-100 syringe (5–10 mg)

Vial	BAC water	Draw
10 mg	1 mL	50–100 unitslarge volume
50 mg	2 mL	20–40 units
50 mg	2.5 mL	25–50 units

On a U-100 syringe, 100 units = 1 mL, and the syringe holds 100 units total. Most people keep a single subcutaneous injection under about 50 units — bigger volumes are usually mixed stronger (less water) or split into two shots. Only mixes that fit in one syringe are shown. Always double-check with the reconstitution calculator.

What it does

A four-amino-acid peptide studied in long-term Russian research for healthy ageing. It appears to influence the pineal gland and melatonin rhythm and has been reported to support telomerase, the enzyme that maintains the protective caps on DNA. What people look into it for: • Restoring a normal sleep-wake rhythm • General healthy-ageing and longevity protocols • Antioxidant and immune support • Skin and overall vitality It is typically run as a short course once or twice a year rather than continuously, and the human data comes from a small number of older studies.

Mechanism

Reported to stimulate telomerase and normalise melatonin rhythm in animal studies.

Storage — lyophilisedwhat's this?

Refrigerate 2-8C, protect from light.

Storage — reconstitutedwhat's this?

Refrigerate 2-8C, use within ~28 days.

Reconstitution noteswhat's this?

Common mix: 10 mg vial + 1 ml bacteriostatic water = 100 mcg per unit, so 5 mg is 50 units and 10 mg fills the syringe at 100 units. A 50 mg vial + 3 ml gives 167 mcg per unit (5 mg ≈ 30 units). Dose at night.

Stacks well with

Popular combinations reported in the community and research literature — not a recommendation. Adding peptides multiplies side-effect risk; check with a clinician.

Commonly reported side effects

Drowsiness
Injection-site irritation

Contraindications noted

Active malignancy
Pregnancy or breastfeeding

Research notes

Human evidence limited to small Russian studies.

Vendors carrying Epitalon

These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.

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Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.