DSIP
Also known as Delta Sleep-Inducing Peptide
Nonapeptide investigated for sleep regulation.
Medical status: Not approved as a medicine.
Also commonly used for (off-label)
- Trouble falling or staying asleep
- Stress and recovery protocols
Off-label and research uses are what people report, not approved indications. Talk to a clinician before using any of them.
How it's taken (route)
a small shot into the fat just under the skin (belly, thigh, or love handle)
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- Documented dose
- 100–700 mcg
- Typical frequency
- Once nightly, 30–60 minutes before bed
- Cycle
- 8 weeks on, 4 off
- Half-life
- ~7-15 minutes
- Common vial sizes
- 2 mg, 5 mg
- Regulatory status
- Not approved for human use.
Dose on a U-100 syringe (100–700 mcg)
| Vial | BAC water | Draw |
|---|---|---|
| 2 mg | 1 mL | 5.0–35 units |
| 5 mg | 2.5 mL | 5.0–35 units |
| 5 mg | 3 mL | 6.0–42 units |
On a U-100 syringe, 100 units = 1 mL, and the syringe holds 100 units total. Most people keep a single subcutaneous injection under about 50 units — bigger volumes are usually mixed stronger (less water) or split into two shots. Only mixes that fit in one syringe are shown. Always double-check with the reconstitution calculator.
What it does
Short for Delta Sleep-Inducing Peptide. It is thought to help the brain shift into deeper, slower-wave sleep and to blunt the body's stress response. What people look into it for: • Falling asleep faster and waking less during the night • More deep, restorative sleep rather than just more hours • Feeling calmer and more resilient under stress • Some reports of reduced chronic pain and easier withdrawal from stimulants Human research is old and small, and results vary a lot between individuals.
Mechanism
Poorly characterised; may modulate delta-wave sleep and corticotropin release.
Storage — lyophilisedwhat's this?
Refrigerate 2-8C, protect from light.
Storage — reconstitutedwhat's this?
Refrigerate 2-8C, use within ~28 days.
Reconstitution noteswhat's this?
Common mix: 5 mg vial + 2.5 ml bacteriostatic water = 20 mcg per unit, so 100 mcg is 5 units, 300 mcg is 15 units and 700 mcg is 35 units. Step up by 100 mcg at a time.
Stacks well with
- EpitalonSleep architecture plus circadian regulation.
- IpamorelinNight-time GH pulses pair naturally with deeper sleep.
Popular combinations reported in the community and research literature — not a recommendation. Adding peptides multiplies side-effect risk; check with a clinician.
Commonly reported side effects
- Grogginess
- Headache
- Vivid dreams
Contraindications noted
- Pregnancy or breastfeeding
Research notes
Evidence is old and inconsistent; effect sizes unclear.
Vendors carrying DSIP
These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.
- PeptideMaxxingpeptidemaxxing.com15% Off(opens in a new window)
- Nexaphnexaph.com(opens in a new window)
- Modified Aminosmodifiedaminos.shop(opens in a new window)
- Penguin Peptidespenguinpeptides.com(opens in a new window)
- Peplair Researchpeplairresearch.shop(opens in a new window)
- Biotech Peptidesbiotechpeptides.com(opens in a new window)
- Sports Technology Labssportstechnologylabs.com(opens in a new window)
- Core Peptidescorepeptides.com(opens in a new window)
- Value Research Labsvalueresearchlabs.com(opens in a new window)
Peptide Streak users get 15% off PeptideMaxxing with code PEPSTREAK.
Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.