cognitivelongevity

Dihexa

Also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, PNB-0408

An oral peptide studied for building new brain connections.

How it's taken (route)

Documented dose
5–20 mg
Typical frequency
Once daily, or split into 2-3 doses
Cycle
10 weeks on, 5 off
Half-life
Long relative to most peptides
Regulatory status
Research chemical — not approved for human use.

No syringe needed

Dihexa is taken oral capsule or tablet, so there is no U-100 syringe draw for it.

What it does

Dihexa is used by people looking for a strong, long-lasting cognitive effect — better memory formation, faster learning, and clearer thinking. It is taken as a capsule, usually in the morning on an empty stomach, in 8-12 week blocks.

Mechanism

Boosts hepatocyte growth factor (HGF) signalling at the c-Met receptor, which drives the formation of new synapses.

Storage — lyophilisedwhat's this?

Store capsules cool and dry.

Storage — reconstitutedwhat's this?

Not applicable — oral capsules.

Reconstitution noteswhat's this?

No mixing needed. 1-4 capsules (5-20 mg) per day, taken on an empty stomach 30 minutes before food. Morning dosing avoids sleep disruption.

Stacks well with

Popular combinations reported in the community and research literature — not a recommendation. Adding peptides multiplies side-effect risk; check with a clinician.

Commonly reported side effects

  • Sleep disturbance if dosed late
  • Headache
  • Overstimulation

Contraindications noted

  • Any active cancer — synapse-growth signalling is not selective

Research notes

Animal work is striking, but there is no published human trial. The growth-factor mechanism is the main reason for caution.

Vendors carrying Dihexa

These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.

Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.

Track this properly

Work out syringe units with the calculator, or set up a full schedule in about a minute.

Reference information only, not medical advice. See our medical disclaimer.