Tesamorelin + Ipamorelin Blend
Also known as Tesamorelin + Ipamorelin, Tesamorelin / Ipamorelin blend
Blended GHRH analogue and ghrelin-mimetic growth hormone secretagogue for body composition and recovery.
Medical status: Not approved as a medicine; sold as a research blend.
Also commonly used for (off-label)
- Visceral fat loss and body recomposition
- Growth hormone support from a single vial
- Recovery and overnight sleep quality
Off-label and research uses are what people report, not approved indications. Talk to a clinician before using any of them.
How it's taken (route)
a small shot into the fat just under the skin (belly, thigh, or love handle)
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- Documented dose
- 1–2 mg
- Typical frequency
- 1 time daily, 5 days on / 2 days off
- Cycle
- 12 weeks on, 4 off
- Half-life
- ~26–38 minutes for Tesamorelin; ~2 hours for Ipamorelin
- Common vial sizes
- 10 mg, 20 mg
- Regulatory status
- Not approved for human use in most jurisdictions.
Dose on a U-100 syringe (1–2 mg)
| Vial | BAC water | Draw |
|---|---|---|
| 10 mg | 2 mL | 20–40 units |
| 10 mg | 2.5 mL | 25–50 units |
| 20 mg | 3 mL | 15–30 units |
| 20 mg | 5 mL | 25–50 units |
On a U-100 syringe, 100 units = 1 mL, and the syringe holds 100 units total. Most people keep a single subcutaneous injection under about 50 units — bigger volumes are usually mixed stronger (less water) or split into two shots. Only mixes that fit in one syringe are shown. Always double-check with the reconstitution calculator.
What it does
A pre-mixed combination of Tesamorelin and Ipamorelin that targets visceral fat loss and growth hormone release together. Tesamorelin is a GHRH analogue that specifically raises growth hormone in the abdominal region, while Ipamorelin mimics ghrelin to trigger a clean GH pulse from the pituitary. The combination is used for body recomposition, visceral fat reduction, and recovery support. What people look into it for: • Reducing visceral belly fat • Supporting lean muscle and recovery • Improving sleep quality and overnight recovery • A simplified protocol from a single vial
Mechanism
Tesamorelin binds GHRH receptors to increase endogenous growth hormone secretion, with a particular effect on visceral adipose tissue. Ipamorelin selectively activates the ghrelin receptor (GHS-R1a) to release an additional GH pulse without meaningfully raising cortisol, prolactin or hunger. The two peptides act through complementary pathways in a single injection.
Storage — lyophilisedwhat's this?
Refrigerate 2-8°C, protect from light.
Storage — reconstitutedwhat's this?
Refrigerate 2-8°C, use within ~28 days.
Reconstitution noteswhat's this?
Common mix: 10 mg total peptide blend + 2 ml bacteriostatic water = 50 mcg per unit. A 1 mg Tesamorelin dose would draw 20 units; the same volume also delivers the blended Ipamorelin component.
Commonly reported side effects
- Injection-site redness
- Water retention
- Head rush
- Hunger
- Drowsiness
- Tingling hands
Contraindications noted
- Active malignancy
- Pregnancy or breastfeeding
- Uncontrolled diabetes
Research notes
Tesamorelin is best known for its research in HIV-associated lipodystrophy; the blend format is commonly used for convenience in body-recomposition protocols.
Vendors carrying Tesamorelin + Ipamorelin Blend
These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.
- Penguin Peptidespenguinpeptides.com(opens in a new window)
- Value Research Labsvalueresearchlabs.com(opens in a new window)
- Biotech Peptidesbiotechpeptides.com(opens in a new window)
- Core Peptidescorepeptides.com(opens in a new window)
- Peplair Researchpeplairresearch.shop(opens in a new window)
Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.