KLOW
Also known as KLOW blend, GHK-Cu/BPC-157/TB-500/KPV blend
Four-peptide blend: GLOW (GHK-Cu, BPC-157, TB-500) plus the anti-inflammatory tripeptide KPV.
Medical status: Not approved as a medicine; sold as a research blend.
Also commonly used for (off-label)
- Recovery where inflammation is part of the picture
- Skin, hair and connective-tissue repair
- Gut and inflammatory complaints (via the KPV component)
Off-label and research uses are what people report, not approved indications. Talk to a clinician before using any of them.
How it's taken (route)
a small shot into the fat just under the skin (belly, thigh, or love handle)
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- Documented dose
- 2300–2700 mcg
- Typical frequency
- Once daily, subcutaneous
- Cycle
- 6 weeks on, 4 off
- Half-life
- Varies by component (GHK-Cu ~1 hour, BPC-157 ~4 hours)
- Common vial sizes
- 80 mg, 100 mg
- Regulatory status
- Not approved for human use; sold as a research compound.
Dose on a U-100 syringe (2300–2700 mcg)
| Vial | BAC water | Draw |
|---|---|---|
| 80 mg | 3 mL | 8.6–10 units |
| 80 mg | 5 mL | 14–17 units |
| 100 mg | 3 mL | 6.9–8.1 units |
| 100 mg | 5 mL | 12–14 units |
On a U-100 syringe, 100 units = 1 mL, and the syringe holds 100 units total. Most people keep a single subcutaneous injection under about 50 units — bigger volumes are usually mixed stronger (less water) or split into two shots. Only mixes that fit in one syringe are shown. Always double-check with the reconstitution calculator.
What it does
KLOW is GLOW with KPV added. The first three peptides cover collagen remodelling, soft-tissue repair and cell migration, while KPV adds an anti-inflammatory arm. It is usually chosen over GLOW when inflammation is part of the picture.
Mechanism
GHK-Cu drives collagen and skin-remodelling gene expression, BPC-157 supports angiogenesis and connective-tissue repair, TB-500 regulates actin and cell motility, and KPV (Lys-Pro-Val, an alpha-MSH fragment) inhibits NF-kB inflammatory signalling. The four-peptide combination itself has not been studied in humans.
Storage — lyophilisedwhat's this?
Refrigerate 2-8C, protect from light.
Storage — reconstitutedwhat's this?
Refrigerate 2-8C, use within ~28 days.
Reconstitution noteswhat's this?
The standard vial is 80 mg (50 mg GHK-Cu + 10 mg each of BPC-157, TB-500 and KPV). Common mix: 80 mg vial + 3 ml bacteriostatic water = about 26.7 mg/ml, so 1 unit on a U-100 syringe (0.01 ml) is roughly 267 mcg of total blend (~167 mcg GHK-Cu and ~33 mcg of each of the others). Ratios vary by supplier — read the label.
Commonly stacked with
- Wolverine stack (BPC-157 + TB-500)
Commonly reported side effects
- Injection-site stinging or redness
- Blue discolouration at the injection site
- Lightheadedness
- Nausea
Contraindications noted
- Wilson disease or copper overload
- Active malignancy (theoretical, via angiogenesis)
- Pregnancy or breastfeeding
Research notes
Copper accumulation from the large GHK-Cu load is the usual reason for the 2-4 week off period. No published trial has evaluated the four-peptide combination. BPC-157 and TB-500 are WADA-prohibited for athletes.
Vendors carrying KLOW
These research suppliers list this compound. Prices, vial sizes and testing vary — always check the current lot certificate before you buy.
- PeptideMaxxingpeptidemaxxing.com15% Off(opens in a new window)
- Penguin Peptidespenguinpeptides.com(opens in a new window)
- Value Research Labsvalueresearchlabs.com(opens in a new window)
- Biotech Peptidesbiotechpeptides.com(opens in a new window)
- Zeptix Labszeptixlabs.com15% Off(opens in a new window)
- Core Peptidescorepeptides.com(opens in a new window)
- Peplair Researchpeplairresearch.shop(opens in a new window)
Peptide Streak users get 15% off PeptideMaxxing with code PEPSTREAK.
Peptide Streak users get 15% off Zeptix Labs with code PEPSTREAK.
Peptide Streak does not sell peptides and is not affiliated with these vendors. Some list metabolic compounds under coded product names.